Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences.

doi:10.1002/ijc.2910570206

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Article

Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences.

International journal of cancer - 15 Apr 1994

Scarpa A, Capelli P, Villaneuva A, Zamboni G, Lluìs F, Accolla R, Mariuzzi G, Capellà G

Abstract excerpt

Seventy-seven pancreatic adenocarcinomas (60 Spanish and 17 Italian) were tested for Ki-ras gene mutations by analysis of polymerase chain reaction amplified sequences. Mutations involving codon 12 (GGT; gly) were detected in 16 Italian and 46 Spanish cases (80.5% in total). All Italian mutations...

Topics

Adenocarcinoma
Base Sequence
Europe
Female
Genes, ras
Humans
Male
Middle Aged
Molecular Sequence Data
Mutation
Pancreatic Neoplasms
Polymerase Chain Reaction

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