Article
Lifetime history of tobacco consumption and K-ras mutations in exocrine pancreatic cancer.
Pancreas - 1 Aug 2007
Crous-Bou Marta, Porta Miquel, López Tomàs, Jariod Manuel, Malats Núria, Alguacil Juan, Morales Eva, Fernandez Esteve, Corominas Josep M, Carrato Alfredo, Guarner Luisa, Real Francisco X
Abstract excerpt
OBJECTIVES: We analyzed the relation between mutations in codon 12 of the K-ras oncogene and lifetime consumption of tobacco in patients with exocrine pancreatic cancer (EPC). METHODS: Incident cases of EPC were prospectively identified and interviewed during hospital admission about smoking and other factors. Exact logistic regression was used to compare EPC cases (N = 107) with and without K-ras mutations...
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