Article
Comparison of mutations of ras oncogene in human pancreatic exocrine and endocrine tumors.
Surgery - 1 Oct 1993
Yashiro T, Fulton N, Hara H, Yasuda K, Montag A, Yashiro N, Straus F, Ito K, Aiyoshi Y, Kaplan E L
Abstract excerpt
BACKGROUND: Ras oncogene mutations have been found in many human cancers; however, pancreatic endocrine tumors have rarely been studied. The purpose of this study was to analyze ras mutations in pancreatic endocrine tumors and to compare these results with the incidence of ras mutations in pancreatic exocrine cancers studied in our laboratory. METHODS: Ras oncogene mutations were studied in 33 foregut endocrine...
Topics
- Adenoma, Islet Cell
- Autoradiography
- Base Sequence
- Genes, ras
- Humans
- Molecular Sequence Data
- Mutation
- Nucleic Acid Hybridization
- Oligonucleotide Probes
- Pancreatic Neoplasms
- Polymerase Chain Reaction