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Article

Oxygen scavenging, NADH oxidase and metronidazole resistance in Helicobacter pylori.

The Journal of antimicrobial chemotherapy - 1 Mar 1997

Smith M A, Edwards D I

Abstract excerpt

Failure of triple-therapy regimes to eradicate Helicobacter pylori from the stomach is thought to be due to the occurrence of a metronidazole-resistant bacterial population. Exposure of metronidazole-resistant (MtzR) strains of H. pylori to an anaerobic environment causes the activation of metronidazole and the loss of resistance. Using metronidazole-sensitive (MtzS) clinical isolates, we selected mutants...

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Identifiers

PMID: 9096184
DOI: 10.1093/jac/39.3.347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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