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Article

rdxA, frxA, and efflux pump in metronidazole-resistant Helicobacter pylori: Their relation to clinical outcomes.

Journal of gastroenterology and hepatology - 1 Mar 2018

Lee Sun Min, Kim Nayoung, Kwon Yong Hwan, Nam Ryoung Hee, Kim Jung Mogg, Park Jong Youn, Lee Yeon Suk, Lee Dong Ho

Abstract excerpt

BACKGROUND AND AIM: rdxA and frxA mutations and enhancement of efflux pump have been suggested as the cause of metronidazole resistance in Helicobacter pylori. This study was performed to investigate the resistance mechanisms related to clinical eradication outcome, and to examine direct involvement of hefA in metronidazole-resistant isolates with intact rdxA and frxA. METHODS: A total of 53 H. pylori-positive...

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PMID: 28748532
DOI: 10.1111/jgh.13906

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rdxA, frxA, and efflux pump in metronidazole-resistant Helicobacter pylori: Their relation to clinical outcomes.PMID 28748532Read ↗

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