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Roles of FrxA and RdxA Nitroreductases of <i>Helicobacter pylori</i> in Susceptibility and Resistance to Metronidazole

1 Sept 2001

Abstract excerpt

The relative importance of the frxA and rdxA nitroreductase genes of Helicobacter pylori in metronidazole (MTZ) susceptibility and resistance has been controversial. Jeong et al. (J. Bacteriol. 182:5082--5090, 2000) had interpreted that Mtz(s) H. pylori were of two types: type I, requiring only inactivation of rdxA to became resistant, and type II, requiring inactivation of both rdxA and frxA to become resistant;...

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PMID: 11489869
DOI: 10.1128/jb.183.17.5155-5162.2001

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Roles of FrxA and RdxA Nitroreductases of <i>Helicobacter pylori</i> in Susceptibility and Resistance to MetronidazolePMID 11489869Read ↗

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