Article
Transfer of voltage independence from a rat olfactory channel to the Drosophila ether-à-go-go K+ channel.
The Journal of general physiology - 1 Mar 1997
Tang C Y, Papazian D M
Abstract excerpt
The S4 segment is an important part of the voltage sensor in voltage-gated ion channels. Cyclic nucleotide-gated channels, which are members of the superfamily of voltage-gated channels, have little inherent sensitivity to voltage despite the presence of an S4 segment. We made chimeras between a voltage-independent rat olfactory channel (rolf) and the voltage-dependent ether-à-go-go K+ channel (eag) to determine...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
