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Article

Essential and non‐redundant roles of p48 (ISGF3γ) and IRF‐1 in both type I and type II interferon responses, as revealed by gene targeting studies

1 Jan 1996

Abstract excerpt

BACKGROUND: Interferons (IFNs) are a class of cytokines which confer cellular resistance against viral infections. Type I (IFN-alpha and -beta) and type II (IFN-gamma) IFNs utilize distinct receptors, the stimulation of which results in the induction of downstream target genes. These target genes usually contain within their promoter region an IFN responsive element, termed ISRE (IFN stimulated response element)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 9078371
DOI: 10.1046/j.1365-2443.1996.08008.x

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