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Article

Maintenance of genomic imprinting at the IGF2 locus in hepatoblastoma.

Cancer research - 15 Oct 1993

Davies S M

Abstract excerpt

Genomic imprinting is the parental allele specific expression of genes and has recently been shown to occur in humans. Evidence for a role for genomic imprinting in human cancer comes from the finding of preferential retention of paternal alleles in embryonal tumors undergoing loss of heterozygosity, e.g., Wilms' tumor and osteogenic sarcoma. Recent studies have demonstrated imprinting of the insulin-like growth...

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Source

Identifiers

PMID: 8402661

Genes

IGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Maintenance of genomic imprinting at the IGF2 locus in hepatoblastoma.PMID 8402661Read ↗

Allelic-expression imbalance of the insulin-like growth factor 2 gene in hepatocellular carcinoma and underlying disease.Semantic proximity Read ↗

Occasional loss of constitutive heterozygosity at 11p15.5 and imprinting relaxation of the IGFII maternal allele in hepatoblastoma.Semantic proximity Read ↗

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Genomic imprinting and carcinogenesis.Semantic proximity Read ↗

Loss of imprinting of human insulin-like growth factor II gene, IGF2, in acute myeloid leukemia.Semantic proximity Read ↗

Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour.Semantic proximity Read ↗

Promoter-specific imprinting of the human insulin-like growth factor-II gene.Semantic proximity Read ↗

Relaxation of imprinted genes in human cancer.Semantic proximity Read ↗

Developmental regulation of genomic imprinting of the IGF2 gene in human liver.Semantic proximity Read ↗

Alterations in the promoter-specific imprinting of the insulin-like growth factor-II gene in Wilms' tumor.Semantic proximity Read ↗

Altered transcriptional regulation of the insulin-like growth factor 2 gene in human hepatocellular carcinoma.Semantic proximity Read ↗

Monoallelic expression of the insulin-like growth factor-2 gene in ovarian cancer.Semantic proximity Read ↗

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