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Article

Differential susceptibility to seizures induced by systemic kainic acid treatment in mature DBA/2J and C57BL/6J mice.

Epilepsia - 1 Mar 1995

Ferraro T N, Golden G T, Smith G G, Berrettini W H

Abstract excerpt

Mature DBA/2J (D2) and C57BL/6J (B6) mice aged 9-10 weeks were studied to determine susceptibility to behavioral seizures induced by kainic acid (KA) and the possible influence exerted by differences in metabolism and blood-brain barrier (BBB) transport. Mice were observed for 4 h after subcutaneous (s.c.) KA injection. Behavioral seizure parameters included latency to first seizure (clonus), latency to...

Topics

Animals
Blood-Brain Barrier
Brain
Disease Models, Animal
Dose-Response Relationship, Drug
Genetic Predisposition to Disease
Kainic Acid
Male
Mice
Mice, Inbred C57BL
Mice, Inbred DBA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Seizures

Species Specificity

Source

Identifiers

PMID: 7614915
DOI: 10.1111/j.1528-1157.1995.tb00999.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7614915-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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