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Article

Optimal weighting scheme for affected sib-pair analysis of sibship data.

Annals of human genetics - 1 Jan 1997

Sham P C, Zhao J H, Curtis D

Abstract excerpt

Application of the affected sib-pair method of linkage analysis to sibships with variable numbers of affected and unaffected members requires a scheme for weighting the contributions from the sibships in the calculation of an overall test statistic. Currently accepted weighting schemes are based on the concepts of independent pairs and Shannon information content. Here, we show that the weighting scheme with...

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Identifiers

PMID: 9066928
DOI: 10.1046/j.1469-1809.1997.6110059.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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