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Article

Cross protective immunity conferred by a marker-free aroA mutant of Pasteurella multocida.

Vaccine - 1 Feb 1997

Homchampa P, Strugnell R A, Adler B

Abstract excerpt

The aroA gene from Pasteurella multocida serotype A:1 (X-73) was cloned by complementation of the Escherichia coli aroA mutant AB2829 with a DNA library constructed in pUC18. The cloned aroA gene was inactivated by deletion of a 300 bp internal sequence and reintroduced by homologous recombination into the chromosome of X-73 and P-1059 (serotype A:3) using a Pasteurella-E. coli shuttle vector pPBA1100. By...

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Identifiers

PMID: 9066039
DOI: 10.1016/s0264-410x(96)00139-9

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