Article
Cross protective immunity conferred by a marker-free aroA mutant of Pasteurella multocida.
Vaccine - 1 Feb 1997
Homchampa P, Strugnell R A, Adler B
Abstract excerpt
The aroA gene from Pasteurella multocida serotype A:1 (X-73) was cloned by complementation of the Escherichia coli aroA mutant AB2829 with a DNA library constructed in pUC18. The cloned aroA gene was inactivated by deletion of a 300 bp internal sequence and reintroduced by homologous recombinatio...
Topics
- 3-Phosphoshikimate 1-Carboxyvinyltransferase
- Alkyl and Aryl Transferases
- Animals
- Bacterial Vaccines
- Biomarkers
- Cloning, Molecular
- Cross Reactions
- Female
- Mice
- Mice, Inbred BALB C
- Mutation
- Pasteurella Infections
- Pasteurella multocida
- Sequence Deletion
- Transferases
- Vaccines, Attenuated
- Virulence
