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Article

Hepatic messenger RNA contents of cytochrome P4502E1 in patients with different P4502E1 genotypes.

Alcohol and alcoholism (Oxford, Oxfordshire). Supplement - 1 Jan 1994

Tsutsumi M, Wang J S, Takase S, Takada A

Abstract excerpt

Since heavy drinkers do not always develop alcoholic liver disease (ALD), genetic factors may be involved. Cytochrome P4502E1 (P4502E1) is the main enzyme that oxidizes ethanol in the non-alcohol dehydrogenase pathway. Recently, the presence of genetic polymorphisms at the 5'-flanking region of this enzyme was confirmed. We recently detected the c2 gene of P4502E1 in most patients with ALD, suggesting that...

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Source

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PMID: 9063815

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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