Article
Genetic factors related to the development of carcinoma in digestive organs in alcoholics.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement - 1 Jan 1993
Tsutsumi M, Takase S, Takada A
Abstract excerpt
Heavy drinkers do not always develop alcoholic liver disease or cancer of the digestive organs, indicating that genetic factors may be involved. Recently, the presence of genetic polymorphisms of cytochrome P4502E1 (2E1) was confirmed. The genotype of 2E1 was separated into three types; type A wh...
Topics
- Alcoholism
- Aldehyde Dehydrogenase
- Carcinoma, Hepatocellular
- Cell Transformation, Neoplastic
- Digestive System Neoplasms
- Genotype
- Humans
- Isoenzymes
- Liver Diseases, Alcoholic
- Liver Neoplasms
- Polymerase Chain Reaction
- Risk Factors
- Smoking