Article
Genetic polymorphisms of genes coding to alcohol-metabolizing enzymes in western Mexicans: association of CYP2E1*c2/CYP2E1*5B allele with cirrhosis and liver function.
Alcoholism, clinical and experimental research - 1 Mar 2012
García-Bañuelos Jesús, Panduro Arturo, Gordillo-Bastidas Daniela, Gordillo-Bastidas Elizabeth, Muñoz-Valle José Francisco, Gurrola-Díaz Carmen M, Sánchez-Enríquez Sergio, Ruiz-Madrigal Bertha, Bastidas-Ramírez Blanca Estela
Abstract excerpt
BACKGROUND: Alcoholic cirrhosis constitutes a major public health problem in the world where ADH1B, ALDH2, and CYP2E1 polymorphisms could be playing an important role. We determined ADH1B*2, ALDH2*2, and CYP2E1*c2 allele frequencies in healthy control individuals (C) and patients with alcoholic cirrhosis (AC) from western Mexico. METHODS: Ninety C and 41 patients with AC were studied. Genotype and allele...
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