Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Survival probability of drug resistant mutants in malaria parasites.

Proceedings. Biological sciences - 22 Jan 1997

Mackinnon M J

Abstract excerpt

This study predicts the ultimate probability of survival of a newly arisen drug resistant mutant in a population of malaria parasites, with a view to understanding what conditions favour the evolution of drug resistance. Using branching process theory and a population genetics transmission model, the probabilities of survival of one- and two-locus new mutants are calculated as functions of the degree of drug...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance
Share to Malaria
Share to Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 9061960
DOI: 10.1098/rspb.1997.0008
PMCID: PMC1688216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Survival probability of drug resistant mutants in malaria parasites.PMID 9061960Read ↗

Accessible mutational trajectories for the evolution of pyrimethamine resistance in the malaria parasite Plasmodium vivax.Semantic proximity Read ↗

The emergence of drug-resistant malaria.Semantic proximity Read ↗

Time of treatment influences the appearance of drug-resistant parasites in Plasmodium falciparum infections.Semantic proximity Read ↗

A computational method for predicting the most likely evolutionary trajectories in the stepwise accumulation of resistance mutations.Semantic proximity Read ↗

The population genetics of drug resistance evolution in natural populations of viral, bacterial and eukaryotic pathogens.Semantic proximity Read ↗

Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population.Semantic proximity Read ↗

The evolutionary epidemiology of multilocus drug resistance.Semantic proximity Read ↗

The evolutionary landscape of antifolate resistance in Plasmodium falciparum.Semantic proximity Read ↗

The dynamics of mutations associated with anti-malarial drug resistance in Plasmodium falciparum.Semantic proximity Read ↗

Evolutionary rescue of a parasite population by mutation rate evolution.Semantic proximity Read ↗

A pivot mutation impedes reverse evolution across an adaptive landscape for drug resistance in Plasmodium vivax.Semantic proximity Read ↗

Ahead of the curve: next generation estimators of drug resistance in malaria infections.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.