Article
Time of treatment influences the appearance of drug-resistant parasites in Plasmodium falciparum infections.
Parasitology - 1 Dec 2001
Gatton M L, Hogarth W, Saul A
Abstract excerpt
A deterministic mathematical model which predicts the probability of developing a new drug-resistant parasite population within the human host is reported. The model incorporates the host's specific antibody response to PfEMP1, and also investigates the influence of chemotherapy on the probability of developing a viable drug-resistant parasite population within the host. Results indicate that early treatment, and...
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