Article
Allelic deletions at chromosome 11q22-q23.1 and 11q25-qterm are frequent in sporadic breast but not colorectal cancers.
Oncogene - 30 Jan 1997
Koreth J, Bakkenist C J, McGee J O
Abstract excerpt
We identified the chromosome 11q23 region as containing a putative tumour suppressor gene(s) frequently deleted in nonfamilial breast and other cancers. To define this region(s) further, we performed a systematic genetic analysis at chromosome 11q14-qterm in sporadic breast and colorectal cancer....
Topics
- Alleles
- Breast Neoplasms
- Chromosome Deletion
- Chromosome Mapping
- Chromosomes, Human, Pair 11
- Colorectal Neoplasms
- DNA, Neoplasm
- Female
- Gene Deletion
- Genes, Tumor Suppressor
- Genetic Markers
- Humans
