Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer.

Article

Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer.

Cancer research - 15 Feb 1996

Davis M, Hitchcock A, Foulkes W D, Campbell I G

Abstract excerpt

Loss of heterozygosity on chromosome 11q23.3-qter is a frequent event in ovarian carcinoma, implying the existence of an important ovarian tumor suppressor gene(s) within the region. To refine a minimum region(s) of loss, 67 ovarian tumors were analyzed for loss of heterozygosity with eight micro...

Topics

Alleles
Chromosome Deletion
Chromosome Mapping
Chromosomes, Human, Pair 11
DNA, Neoplasm
Female
Genetic Markers
Humans
Neoplasm Staging
Ovarian Neoplasms

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