Article
Refinement of two chromosome 11q regions of loss of heterozygosity in ovarian cancer.
Cancer research - 15 Feb 1996
Davis M, Hitchcock A, Foulkes W D, Campbell I G
Abstract excerpt
Loss of heterozygosity on chromosome 11q23.3-qter is a frequent event in ovarian carcinoma, implying the existence of an important ovarian tumor suppressor gene(s) within the region. To refine a minimum region(s) of loss, 67 ovarian tumors were analyzed for loss of heterozygosity with eight microsatellite markers spanning 11q23.3-qter. Forty tumors (61%) demonstrated allelic losses. Twenty-seven of these had...
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