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Article

Somatic mutations of the PPP2R1B candidate tumor suppressor gene at chromosome 11q23 are infrequent in ovarian carcinomas.

Neoplasia (New York, N.Y.) - 1 Oct 1999

Wu R, Connolly D C, Ren X, Fearon E R, Cho K R

Abstract excerpt

Previous studies have demonstrated frequent allelic losses of distal chromosome 11q in ovarian carcinomas. The tumor suppressor gene(s) presumably targeted by these losses have not yet been identified. PPP2R1B is a candidate tumor suppressor gene at 11q23 that has recently been shown to be mutated in a subset of colorectal and lung cancers. We evaluated 5 ovarian carcinoma cell lines and 27 primary ovarian...

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Identifiers

PMID: 10935485
DOI: 10.1038/sj.neo.7900042
PMCID: PMC1508096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Somatic mutations of the PPP2R1B candidate tumor suppressor gene at chromosome 11q23 are infrequent in ovarian carcinomas.PMID 10935485Read ↗

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The BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.Semantic proximity Read ↗

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