Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of transforming growth factor beta on rat hepatocyte cell lines depends upon the state of tumorigenic progression.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Apr 1996

Reeder M K, Isom H C

Abstract excerpt

The effect of transforming growth factor beta (TGF-beta) on morphology, actin cytoskeleton organization, anchorage-dependent proliferation, anchorage-independent proliferation, and alpha-fetoprotein secretion in a series of related hepatocyte-derived cell lines was measured. We reported previously that TGF-beta 1 partially suppressed the transformed phenotype of a ras- transformed SV40-immortalized hepatocyte...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to Cell Division

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Phenotype

Share to Time Factors

Source

Identifiers

PMID: 9052986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of transforming growth factor beta on rat hepatocyte cell lines depends upon the state of tumorigenic progression.PMID 9052986Read ↗

Transforming growth factor beta 1 suppresses transformation in hepatocytes by regulating alpha 1 beta 1 integrin expression.Semantic proximity Read ↗

Establishment and characterization of differentiated, nontransformed hepatocyte cell lines derived from mice transgenic for transforming growth factor alpha.Semantic proximity Read ↗

Spontaneous transformation of an immortalized hepatocyte cell line: potential role of a nuclear protease.Semantic proximity Read ↗

Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-beta1 and Ha-Ras: steps towards invasiveness.Semantic proximity Read ↗

ras transformation of simian virus 40-immortalized rat hepatocytes: an in vitro model of hepatocarcinogenesis.Semantic proximity Read ↗

Phenotypic modulation of keratins, vimentin, and alpha-fetoprotein in cultured rat liver epithelial cells after chemical, oncogene, and spontaneous transformation.Semantic proximity Read ↗

TGFbeta induces apoptosis and EMT in primary mouse hepatocytes independently of p53, p21Cip1 or Rb status.Semantic proximity Read ↗

Distinct dedifferentiation processes affect caveolin-1 expression in hepatocytesSemantic proximity Read ↗

Hepatocyte growth factor induces proliferation and morphogenesis in nonparenchymal epithelial liver cellsSemantic proximity Read ↗

Transforming growth factor beta 1 promotes spontaneous transformation of cultured rat liver epithelial cells.Semantic proximity Read ↗

Development of an in vitro model of tumor progression using v-raf and v-raf/v-myc transformed rat liver epithelial cells: correlation of tumorigenicity with the downregulation of specific proteins.Semantic proximity Read ↗

Fas expression prevents cholangiocarcinoma tumor growth.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.