Transforming growth factor beta 1 promotes spontaneous transformation of cultured rat liver epithelial cells.

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Article

Transforming growth factor beta 1 promotes spontaneous transformation of cultured rat liver epithelial cells.

Cancer research - 1 Dec 1994

Zhang X, Wang T, Batist G, Tsao M S

Abstract excerpt

The neoplastic transformation of cultured rat liver epithelial cells by various means has consistently been associated with the development of resistance to the mito-inhibitory effect of transforming growth factor beta (TGF-beta), suggesting that such phenotype plays a mechanistic role during the...

Topics

ATP Binding Cassette Transporter, Subfamily B, Member 1
Animals
Cell Transformation, Neoplastic
Cells, Cultured
Drug Resistance, Multiple
Epithelium
Liver
Phenotype
RNA, Messenger
Rats
Rats, Inbred F344
Transforming Growth Factor beta

Source

Open in PubMed

Identifiers

PMID: 7954458

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7954458-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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