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Article

Transforming growth factor beta 1 promotes spontaneous transformation of cultured rat liver epithelial cells.

Cancer research - 1 Dec 1994

Zhang X, Wang T, Batist G, Tsao M S

Abstract excerpt

The neoplastic transformation of cultured rat liver epithelial cells by various means has consistently been associated with the development of resistance to the mito-inhibitory effect of transforming growth factor beta (TGF-beta), suggesting that such phenotype plays a mechanistic role during the transformation of these cells. We have studied the induction of the "TGF-beta-resistant" phenotype in a clonal strain...

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PMID: 7954458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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