Article
Fas expression prevents cholangiocarcinoma tumor growth.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Jan 1999
Pickens A, Pan G, McDonald J M, Vickers S M
Abstract excerpt
Cholangiocarcinoma continues to have a dismal prognosis with an overall survival rate of less than 10%. An increased understanding of the molecular oncogenesis of this tumor is needed. Fas/APO-1 (CD95) receptor and Fas ligand have been implicated as key factors in apoptosis. In this study we have examined the role of the Fas receptor in the growth of cholangiocarcinoma. The purpose of this study was to evaluate...
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