Article
Phenotypic modulation of keratins, vimentin, and alpha-fetoprotein in cultured rat liver epithelial cells after chemical, oncogene, and spontaneous transformation.
Journal of cellular physiology - 1 Jun 1994
Bisgaard H C, Ton P T, Nagy P, Thorgeirsson S S
Abstract excerpt
Several lines of evidence have indicated that rat liver epithelial (RLE) cell lines may be related to a dormant stem cell compartment in the liver in vivo. We have demonstrated that keratin 14 (K14) is expressed together with vimentin in undifferentiated RLE cells. However, upon spontaneous trans...
Topics
- Animals
- Cell Line
- Cell Nucleus
- Cell Transformation, Neoplastic
- Cells, Cultured
- Epithelium
- Female
- Gene Expression
- Genes, myc
- Keratins
- Liver
- Mice
- Mice, Nude
- Oncogene Proteins v-raf
- Oncogenes
- Phenotype
- Protein Biosynthesis
- Rats