Article
Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors.
Development (Cambridge, England) - 1 Feb 1997
Berry L W, Westlund B, Schedl T
Abstract excerpt
Caenorhabditis elegans germ-line proliferation is controlled by an inductive interaction between the somatic distal tip cell and the germ line. GLP-1, a member of the Notch family of transmembrane receptors, is required continuously in the germ line to transduce the proliferative signal. In the absence of GLP-1, all proliferative germ cells exit the mitotic cell cycle and enter meiotic prophase. We have...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.