Article
Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors.
Development (Cambridge, England) - 1 Feb 1997
Berry L W, Westlund B, Schedl T
Abstract excerpt
Caenorhabditis elegans germ-line proliferation is controlled by an inductive interaction between the somatic distal tip cell and the germ line. GLP-1, a member of the Notch family of transmembrane receptors, is required continuously in the germ line to transduce the proliferative signal. In the a...
Topics
- Animals
- Animals, Genetically Modified
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation
- Cell Division
- Disorders of Sex Development
- Female
- Gene Expression Regulation
- Gene Transfer Techniques
- Germ Cells
