Article
Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats.
Nature - 12 Aug 1993
Roehl H, Kimble J
Abstract excerpt
The homologous proteins GLP-1 and LIN-12 are required for cell interactions during nematode development. glp-1 and lin-12 are members of a gene family that includes Drosophila Notch and several vertebrate homologues. The members of this family have a single transmembrane domain and a similar arrangement of repeated amino-acid motifs (see Fig. 1). The mechanism by which proteins in this family function is not...
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