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Article

Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans.

Nature - 29 Aug 1991

Mango S E, Maine E M, Kimble J

Abstract excerpt

The glp-1 and lin-12 genes encode homologous transmembrane proteins that may act as receptors for cell interactions during development. The glp-1 product is required for induction of germ-line proliferation and for embryogenesis. By contrast, lin-12 mediates somatic cell interactions, including those between the precursor cells that form the vulval hypodermis (VPCs). Here we analyse an unusual allele of glp-1,...

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PMID: 1881436
DOI: 10.1038/352811a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans.PMID 1881436Read ↗

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