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Article

The establishment of Caenorhabditis elegans germline pattern is controlled by overlapping proximal and distal somatic gonad signals.

Developmental biology - 15 Jul 2003

Pepper Anita S-R, Lo Te Wen, Killian Darrell J, Hall David H, Hubbard E Jane Albert

Abstract excerpt

We investigated the control of proliferation and differentiation in the larval Caenorhabditis elegans hermaphrodite germ line through analysis of glp-1 and lag-2 mutants, cell ablations, and ultrastructural data. After the first several rounds of germ cell division, GLP-1, a receptor of the LIN-12/Notch family, governs germline proliferation. We analyzed the proximal proliferation (Pro) phenotype in glp-1(ar202)...

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PMID: 12871705
DOI: 10.1016/s0012-1606(03)00203-3

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