Article
Phenotypical and functional differences of tumor-infiltrating lymphocytes from human colorectal cancers induced by costimulation with rIL-2 and rIL-4 in vitro.
Anticancer research - 1 Jan 2000
Keller H, Wimmenauer S, Rahner S, Von Kleist S, Farthmann E H
Abstract excerpt
The influence of recombinant human interleukin-4 (rIL-4) on the proliferation and cytotoxic activity of tumor-infiltrating lymphocytes (TIL) from human colorectal cancers was investigated TIL and peripheral blood lymphocytes (PBL) were cultured for 3-5 weeks. Under simultaneous stimulation with r...
Topics
- Adult
- Aged
- Cell Division
- Colorectal Neoplasms
- Female
- Humans
- Interleukin-2
- Interleukin-4
- Lymphocyte Subsets
- Lymphocytes, Tumor-Infiltrating
- Male
- Middle Aged
- Phenotype
- Recombinant Proteins
- T-Lymphocytes, Cytotoxic
