Article
TIL from renal-cell carcinoma: restimulation with tumor influences proliferation and cytolytic activity.
International journal of cancer - 15 Jan 1990
Alexander J, Rayman P, Edinger M, Connelly R, Tubbs R, Bukowski R, Pontes E, Finke J
Abstract excerpt
TIL were cultured from human renal-cell carcinoma (RCC) in 1,000 U/ml rIL2 and restimulated with autologous tumor in efforts to establish which conditions would best expand the number of lymphocytes cytotoxic for autologous tumor. Greater cell yields resulted from multiple restimulations of TIL w...
Topics
- Adult
- Aged
- Carcinoma, Renal Cell
- Cell Division
- Cell Line
- Cell Separation
- Cytotoxicity, Immunologic
- Female
- Humans
- Kidney Neoplasms
- Lymphocyte Activation
- Lymphocytes
- Male
- Middle Aged
- Phenotype
- Tumor Cells, Cultured