Autologous tumour-specific cytotoxic T-cell clone established from tumour-infiltrating lymphocytes (TIL) of malignant ascites in the absence of recombinant interleukin 2(rIL2): activation by autologous tumour cell alone.

doi:10.1007/BF01877383

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Autologous tumour-specific cytotoxic T-cell clone established from tumour-infiltrating lymphocytes (TIL) of malignant ascites in the absence of recombinant interleukin 2(rIL2): activation by autologous tumour cell alone.

Biotherapy (Dordrecht, Netherlands) - 1 Jan 1993

Katano M, Nagumo F, Kubota E, Yamamoto H, Matsuo T, Hisatsugu T, Tadano J

Abstract excerpt

Mixtures of tumour infiltrating lymphocytes (TIL) and tumour cells collected from malignant ascites of a patient with pancreatic cancer were cultured using a microplate without recombinant interleukin 2(rIL2). TIL rapidly proliferated from 21-51 days after the initiation of culture in 20 out of 3...

Topics

Aged
Antigens, Surface
Ascitic Fluid
CD8 Antigens
Clone Cells
Cytokines
Cytotoxicity, Immunologic
Humans
Interleukin-2
Kinetics
Lymphocyte Activation
Lymphocytes, Tumor-Infiltrating
Male
Pancreatic Neoplasms

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Recombinant Proteins

T-Lymphocytes, Cytotoxic

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 8507542
DOI: 10.1007/BF01877383

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8507542-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.