Article
Phenotyping of human tumor-infiltrating lymphocytes before and after exposure to different in vitro stimulation conditions.
Anticancer research - 1 Jan 2000
Wimmenauer S, Wintzer H O, von Kleist S
Abstract excerpt
Tumor-infiltrating lymphocytes (TiL) and autologous peripheral blood lymphocytes (PBL), mainly from breast and kidney tumor patients were cultivated with high- and low-dose rIL-2 under addition of autologous tumor cells or nonmalignant epithelial cells. Tumor cells added to TIL-cultures induced an additional proliferative response. Before cultivation, CD8+ and CD25+ lymphocytes were more frequent in TIL when...
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