Identification of a novel CD56- lymphokine-activated killer cell precursor in cancer patients receiving recombinant interleukin 2.

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Article

Identification of a novel CD56- lymphokine-activated killer cell precursor in cancer patients receiving recombinant interleukin 2.

Cancer research - 15 Nov 1992

McKenzie R S, Simms P E, Helfrich B A, Fisher R I, Ellis T M

Abstract excerpt

Circulating lymphokine-activated killer (LAK) cell activity in cancer patients receiving recombinant interleukin 2 (rIL-2) therapy is confined to cells expressing the CD56- surface marker. However, CD56- cells from these patients but not normal individuals have been reported to exhibit LAK cytotoxicity only following in vitro activation with rIL-2. Studies were performed to document the existence of CD56- LAK...

Topics

Antigens, CD
Antigens, Differentiation, T-Lymphocyte
CD56 Antigen
Carcinoma, Renal Cell
Cell Separation
Hematopoietic Stem Cells
Humans
Interleukin-2
Kidney Neoplasms
Killer Cells, Lymphokine-Activated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Killer Cells, Natural

Lymphocyte Subsets

Lymphocytes

Melanoma

Phenotype

Receptors, IgG

Recombinant Proteins

Source

Open in PubMed

Identifiers

PMID: 1384959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1384959-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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