Article
Time course of changes in phenotypes of cultured tumor-infiltrating lymphocytes isolated from human colorectal cancer.
Gastroenterologia Japonica - 1 Apr 1990
Shimazaki M, Ninomiya M, Muto Y, Saito K, Moriwaki H
Abstract excerpt
A study was conducted to investigate the time course of changes in phenotypes of cultured tumor-infiltrating lymphocytes (TIL) isolated from 5 patients with colorectal cancer. Following initial incubation with protein phytohemagglutinin (PHA-P, final concentration 0.1 w/v%), one of the inducers of interleukin-2 (IL-2) receptor, and recombinant interleukin-2 (rIL-2, 1000U/ml) for 3 days, TIL was further cultured...
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