Article
Phenotypic and functional modulation of interleukin-2-activated peripheral blood mononuclear cells by anti-CD3 and anti-CD28 antibody.
Lymphokine and cytokine research - 1 Aug 1993
Yoshino I, Yano T, Miyamoto M, Sugimachi K, Kimura G, Nomoto K
Abstract excerpt
For effective adoptive cancer immunotherapy, not only killer lymphocytes (cytotoxic T cells or NK cells) but also helper T cells are considered to be beneficial. The conventional culture of human lymphocytes with high-dose of recombinant interleukin -2 (rIL-2) yields a high proportion of killer c...
Topics
- Actins
- Antibodies, Monoclonal
- Base Sequence
- CD28 Antigens
- CD3 Complex
- Cells, Cultured
- Culture Techniques
- Cytokines
- Cytotoxicity, Immunologic
- DNA Primers
- Humans
- Interferon-gamma
- Interleukin-2
- Interleukin-3
- Interleukin-4
- Interleukin-6
- Lymphocyte Subsets
- Lymphocytes