Cytological characteristics of human glioma-infiltrating lymphocytes stimulated with recombinant interleukin 2 and an anti-CD3 antibody.

doi:10.1111/j.1349-7006.1991.tb01851.x

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Article

Cytological characteristics of human glioma-infiltrating lymphocytes stimulated with recombinant interleukin 2 and an anti-CD3 antibody.

Japanese journal of cancer research : Gann - 1 Mar 1991

Kikuchi T, Watanabe M, Ohno T

Abstract excerpt

Tumor-infiltrating lymphocytes (TIL) were generated from 10 glioma specimens by using recombinant interleukin-2 and an anti-CD3 antibody (CD3 + TILs). We obtained more than 1 x 10(9) cells in 5 cases, more than 5 x 10(8) cells in 2 cases, and about 1 x 10(8) cells in 3 cases during three weeks of incubation from small specimens ranging in weight from 0.5 to 2.0 g. In 4 cases, TILs were expanded following...

Topics

Adult
Aged
Antibodies, Monoclonal
Antigens, CD
Antigens, Differentiation, T-Lymphocyte
Astrocytoma
CD3 Complex
Cell Division
Child
Cytotoxicity, Immunologic
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Flow Cytometry

Glioma

Humans

Immunosuppression Therapy

Interleukin-2

Killer Cells, Lymphokine-Activated

Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 1827092
DOI: 10.1111/j.1349-7006.1991.tb01851.x
PMCID: PMC5918394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1827092-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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