Article
Role of positive and negative cis-regulatory elements in the transcriptional activation of the lysozyme locus in developing macrophages of transgenic mice.
The Journal of biological chemistry - 28 Feb 1997
Jägle U, Müller A M, Kohler H, Bonifer C
Abstract excerpt
Expression of the chicken lysozyme locus in macrophages is regulated by at least six different positive and negative cis-regulatory elements. Chromatin of the chicken lysozyme locus is gradually reorganized during macrophage differentiation, indicating that each cis-regulatory element is activate...
Topics
- Animals
- Cell Differentiation
- Chickens
- Hypoxanthine Phosphoribosyltransferase
- Interleukin-3
- Macrophage Colony-Stimulating Factor
- Macrophages
- Mice
- Mice, Transgenic
- Muramidase
- Phenotype
- RNA, Messenger
- Transcription Factors