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Article

Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding.

Nucleic acids research - 11 Dec 1995

Nickel J, Short M L, Schmitz A, Eggert M, Renkawitz R

Abstract excerpt

Expression of the mouse M-lysozyme gene is a specific marker for the differentiation of macrophage/granulocyte cell lineages. Analysis of the mechanisms regulating M-lysozyme gene expression revealed an enhancer element in the 3'-flanking region of the gene, termed the M-lysozyme downstream enhancer (MLDE). Here we demonstrate that the nuclear factors binding to MLDE are present in all tested myeloid and...

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Identifiers

PMID: 8532519
DOI: 10.1093/nar/23.23.4785
PMCID: PMC307465

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