Article
Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster.
Science (New York, N.Y.) - 8 Mar 1996
Ferradini L, Gu H, De Smet A, Rajewsky K, Reynaud C A, Weill J C
Abstract excerpt
Transcriptional regulatory elements have been shown to be necessary but not sufficient for the developmental regulation of immunoglobulin gene rearrangement in mouse precursor B cells. In the chicken lambda light chain locus, additional elements in the V-J intervening sequence are involved in neg...
Topics
- Alleles
- Animals
- B-Lymphocytes
- Base Sequence
- Chimera
- Enhancer Elements, Genetic
- Gene Rearrangement, B-Lymphocyte
- Gene Rearrangement, T-Lymphocyte
- Gene Targeting
- Genes, Immunoglobulin
- Immunoglobulin J-Chains
- Immunoglobulin Variable Region
- Immunoglobulin kappa-Chains
- Introns
- Mice
- Mice, Inbred C57BL
- Mice, SCID
- Molecular Sequence Data