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Article

Rearrangement-enhancing element upstream of the mouse immunoglobulin kappa chain J cluster.

Science (New York, N.Y.) - 8 Mar 1996

Ferradini L, Gu H, De Smet A, Rajewsky K, Reynaud C A, Weill J C

Abstract excerpt

Transcriptional regulatory elements have been shown to be necessary but not sufficient for the developmental regulation of immunoglobulin gene rearrangement in mouse precursor B cells. In the chicken lambda light chain locus, additional elements in the V-J intervening sequence are involved in negative and positive regulation of rearrangement. Here, mutation of the mouse homolog of a chicken element, located in...

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Identifiers

PMID: 8596914
DOI: 10.1126/science.271.5254.1416

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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