Article
Analysis of an approach to oviduct-specific expression of modified chicken lysozyme genes.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Feb 2005
Shimizu Mamiko, Losos Jan K, Gibbins Ann M Verrinder
Abstract excerpt
The -2.7 kb enhancer (E) element of the chicken lysozyme gene domain appears to govern expression of the gene in macrophages but not in oviduct tubular gland cells, the only other site of lysozyme expression. The ultimate goal of our research was to determine whether lysozyme domain variants could be developed that would mainly be expressed in the oviduct so that transgenic birds could be produced that would...
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