Article
Lung cancer in Mexican-Americans and African-Americans is associated with the wild-type genotype of the NAD(P)H: quinone oxidoreductase polymorphism.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 1997
Wiencke J K, Spitz M R, McMillan A, Kelsey K T
Abstract excerpt
Age-adjusted incidence rates for lung cancer are significantly lower for Hispanics compared with non-Hispanic whites or African-Americans; differences in genetic susceptibility have been postulated as one explanation for these ethnic differences. Recently, a polymorphism of the gene encoding NAD(...
Topics
- Adult
- Aged
- Black People
- DNA
- Female
- Gene Frequency
- Genotype
- Humans
- Logistic Models
- Lung Neoplasms
- Male
- Mexican Americans
- Middle Aged
- Multivariate Analysis
- NAD(P)H Dehydrogenase (Quinone)
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Risk Factors