Article
The NQO1 C609T polymorphism and risk of lung cancer: a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Liu Yin, Zhang Deping
Abstract excerpt
OBJECTIVE: NAD(P)H: quinone oxidoreductase 1 (NQO1) is a cytosolic flavoprotein that catalyzes the two- electron reduction of quinoid compounds into hydroquinones. A single base substitution (C?T) polymorphism at 609 in the NQO1 gene reduces quinone reductase activity. Published data on the assoc...
Topics
- Alleles
- Asian People
- China
- Genetic Predisposition to Disease
- Genotype
- Humans
- Lung Neoplasms
- NAD(P)H Dehydrogenase (Quinone)
- Polymorphism, Single Nucleotide
- Risk
- Risk Factors