Article
NAD(P)H: quinone oxidoreductase polymorphism and lung cancer in Taiwan.
Journal of toxicology and environmental health. Part A - 29 Oct 1999
Lin P, Wang H J, Lee H, Lee H S, Wang S L, Hsueh Y M, Tsai K J, Chen C Y
Abstract excerpt
Lung cancer is one of the leading causes of death in Taiwan since 1996. Genetic variation in metabolic activation or detoxification enzymes has been associated with the occurrence of lung cancer. NAD(P)H:quinone oxidoreductase (NQO1) enzyme is a cytosolic two-electron reductase thought to be involved in bioactivation and detoxification of environmental carcinogens. The possible association between NQO1 genetic...
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