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Article

NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 May 2006

Chao Chun, Zhang Zuo-Feng, Berthiller Julien, Boffetta Paolo, Hashibe Mia

Abstract excerpt

UNLABELLED: NAD(P)H:quinone oxidoreductase 1 (NQO1) is a cytosolic enzyme that catalyzes the two-electron reduction of quinoid compounds into hydroquinones, their less toxic form. A sequence variant at position 609 (C --> T) in the NQO1 gene encodes an enzyme with reduced quinone reductase activity in vitro and thus was hypothesized to affect cancer susceptibility. We conducted meta-analyses focusing on three...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16702380
DOI: 10.1158/1055-9965.EPI-05-0899

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis.PMID 16702380Read ↗

The association between NQO1 Pro187Ser polymorphism and bladder cancer susceptibility: a meta-analysis of 15 studies.Semantic proximity Read ↗

The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive meta-analysis.Semantic proximity Read ↗

Association between NAD(P)H:quinone oxidoreductase 1 rs1800566 polymorphism and risk of bladder cancer.Semantic proximity Read ↗

The NQO1 C609T polymorphism and risk of lung cancer: a meta-analysis.Semantic proximity Read ↗

Association between NQO1 Pro187Ser polymorphism and esophageal cancer: a meta-analysis.Semantic proximity Read ↗

Association between NQO1 C609T polymorphism and bladder cancer susceptibility: a systemic review and meta-analysis.Semantic proximity Read ↗

The NQO1 rs1800566 polymorphism and risk of bladder cancer: evidence from 6,169 subjects.Semantic proximity Read ↗

An association between a NQO1 genetic polymorphism and risk of lung cancer.Semantic proximity Read ↗

NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T polymorphism and lung cancer risk: a meta-analysis.Semantic proximity Read ↗

The NQO1 Pro187Ser polymorphism and breast cancer susceptibility: evidence from an updated meta-analysis.Semantic proximity Read ↗

Association of bladder cancer risk with an NAD(P)H:quinone oxidoreductase polymorphism in an ethnic Kashmiri population.Semantic proximity Read ↗

The association between NQO1 Pro187Ser polymorphism and urinary system cancer susceptibility: a meta-analysis of 22 studies.Semantic proximity Read ↗

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