Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxidoreductase 1.

doi:10.1097/00008571-199902000-00015

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Article

Genotype-phenotype relationships in studies of a polymorphism in NAD(P)H:quinone oxidoreductase 1.

Pharmacogenetics - 1 Feb 1999

Siegel D, McGuinness S M, Winski S L, Ross D

Abstract excerpt

The NAD(P)H:quinone oxidoreductase 1 (NQO1) genotype-phenotype relationship was examined in individuals with a polymorphism in NQO1. The polymorphism comprises a C to T base change at position 609 of the human NQO1 cDNA (C609T) and codes for a proline to serine substitution in the amino acid stru...

Topics

Blotting, Western
Genotype
Humans
Immunohistochemistry
NAD(P)H Dehydrogenase (Quinone)
Phenotype
Polymerase Chain Reaction
Polymorphism, Genetic
Tumor Cells, Cultured

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