Article
Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli.
Molecular and cellular biology - 1 Mar 1997
Courtois G, Whiteside S T, Sibley C H, Israel A
Abstract excerpt
Numerous genes required during the immune or inflammation response as well as the adhesion process are regulated by nuclear factor kappaB (NF-kappaB). Associated with its inhibitor, I kappaB, NF-kappaB resides as an inactive form in the cytoplasm. Upon stimulation by various agents, I kappaB is p...
Topics
- Animals
- Antioxidants
- B-Lymphocytes
- DNA-Binding Proteins
- Gene Products, tax
- Human T-lymphotropic virus 1
- Humans
- Hybrid Cells
- I-kappa B Proteins
- Lipopolysaccharides
- Mice
- Mutation
- NF-KappaB Inhibitor alpha
- NF-kappa B
- NF-kappa B p50 Subunit
- Oxidation-Reduction
- Phosphorylation
- Pyrrolidines