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Article

Characterization of a mutant cell line that does not activate NF-kappaB in response to multiple stimuli.

Molecular and cellular biology - 1 Mar 1997

Courtois G, Whiteside S T, Sibley C H, Israel A

Abstract excerpt

Numerous genes required during the immune or inflammation response as well as the adhesion process are regulated by nuclear factor kappaB (NF-kappaB). Associated with its inhibitor, I kappaB, NF-kappaB resides as an inactive form in the cytoplasm. Upon stimulation by various agents, I kappaB is proteolyzed and NF-kappaB translocates to the nucleus, where it activates its target genes. The transduction pathways...

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Identifiers

PMID: 9032271
DOI: 10.1128/MCB.17.3.1441
PMCID: PMC231869

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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