Article
Differentiation of murine pre-B cell line by an adjuvant muramyl peptide via NF-kappa B activation.
Immunobiology - 1 Aug 1995
Cohen L Y, Courtois G, Parant M A
Abstract excerpt
Muramyl dipeptide (MDP) induces NF-kappa B activation in the murine pre-B cell line 70Z/3, increases the expression of surface immunoglobulins, and potentiates the response to other inducers such as LPS or IL-1. In the present study we investigated whether NF-kappa B activation was related to the MDP-stimulated immunoglobulin expression. In a gel shift assay our results confirmed that MDP but not MDP(D,D), an...
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