Two different IFN-gamma nonresponsive variants derived from the B-cell lymphoma 70Z/3.

doi:10.1007/BF00167080

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Article

Two different IFN-gamma nonresponsive variants derived from the B-cell lymphoma 70Z/3.

Immunogenetics - 1 Jan 1994

Rhodes L D, Paull A T, Sibley C H

Abstract excerpt

The kappa immunoglobulin (Igk) light chain locus is transcriptionally silent in the mouse B-cell lymphoma 70Z/3. However, exposure to lipopolysaccharide (LPS) or interferon-gamma (IFN) causes a marked increase in Igk transcription. By immunoselection, we isolated two variants that are nonresponsi...

Topics

Animals
B-Lymphocytes
Base Sequence
DNA
DNA-Binding Proteins
Down-Regulation
Enhancer Elements, Genetic
Genetic Variation
Immunoglobulin kappa-Chains
Interferon-gamma
Introns
Lipopolysaccharides
Mice
Molecular Sequence Data
NF-kappa B
Octamer Transcription Factor-2
Protein Binding
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 8039828
DOI: 10.1007/BF00167080

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8039828-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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