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Article

Activation of Nuclear Factor κB by Different Agents

1 Dec 2006

Abstract excerpt

The transcription factor nuclear factor kappaB (NF-kappaB) or other components of this pathway have been identified as possible therapeutic targets in inflammatory processes, cancer, and autoimmune diseases. In order to clarify the role of NF-kappaB in epithelial cells in response to different stresses, a cell-based screening assay for activation of NF-kappaB-dependent gene transcription in human embryonic kidney...

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Identifiers

PMID: 17341614
DOI: 10.1196/annals.1378.066

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