Article
Functional characterization of the NF-kappa B p65 transcriptional activator and an alternatively spliced derivative.
Molecular and cellular biology - 1 Feb 1992
Ruben S M, Narayanan R, Klement J F, Chen C H, Rosen C A
Abstract excerpt
The NF-kappa B transcription factor complex is composed of two proteins, designated p50 and p65, both having considerable homology to the product of the rel oncogene. We present evidence that the p65 subunit is a potent transcriptional activator in the apparent absence of the p50 subunit, consist...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Cell Line
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression
- Humans
- Leucine Zippers
- Macromolecular Substances
- Mice
- Molecular Sequence Data
- Mutation
- NF-kappa B
- Peptide Mapping
- Plasmids
- Polymerase Chain Reaction